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Research Achievements

Publications (English)

2017
Development of a Novel Zebrafish Model for Type 2 Diabetes Mellitus.
Zang L, Shimada Y*, Nishimura N.
Sci Rep. 2017;7:1461. *equally contributed first author.

Potential protective function of the sterol regulatory element binding factor 1–fatty acid desaturase 1/2 axis in early-stage age-related macular degeneration.
Ashikawa Y, Nishimura Y, Okabe S, Sato Y, Yuge M, Tada T, Miyao H, Murakami S, Kawaguchi K, Sasagawa S, Shimada Y, Tanaka T.
Heliyon. 2017;3:3.
2016
Application of Coiled Coil Peptides in Liposomal Anti-Cancer Drug Delivery Using a Zebrafish Xenograft Model.
Yang J, Shimada Y*, Olsthoorn RC, Snaar-Jagalska BE, Spaink HP, Kros A.
ACS Nano. 2016;10:7428-7435. *equally contributed first author

Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs.
Inoue A, Nishimura Y, Matsumoto N, Umemoto N, Shimada Y, Maruyama T, Kayasuga K, Morihara M, Katagi J, Shiroya T, Hirota Y, Kim S, Tanaka T.
Fundam. Toxicol. Sci. 2016;3:79-87.

Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish.
Zhang B, Shimada Y*, Hirota T, Ariyoshi M, Kuroyanagi J, Nishimura Y, Tanaka T.
Transl Res. 2016;170:89-98 *equally contributed first author

Conferences

2017/12/6-8 Consortium of Biological Science (ConBio 2017)
Comparative Gut Microbiome Analysis of Type 2 Diabetes Mellitus Model of Zebrafish
Yasuhito Shimada, Fumiyoshi Okazaki, Liqing Zang, Hiroko Nakayama, Norihiro Nishimura

Screening of natural compounds produced by soil microflora against human colon cancer
Shunsuke Ichikawa, Ayami Nishida, Fumiyoshi Okazaki, Hiroko Nakayama, Norihiro Nishimura, Yasuhito Shimada
2017/11/24 The 132th Kinki Regional Meeting of The Japanese Pharmacological Society
日本薬用植物エキスライブラリーを用いた骨転移性前立腺がん治療薬探索
島田 康人、中山 寛子、山田 英嗣、渕野 裕之、小川 琢也、西村 訓弘
2017/11/2 The 3rd Zebrafish Drug Discovery Meeting
がん細胞移植ゼブラフィッシュの新たな研究展開
島田 康人、山田 英嗣、中山 寛子、岡崎 文美、西村 訓弘、田中 利男

ゼブラフィッシュを用いた網膜疾患創薬研究
西村 有平、芦川 芳史、笹川 翔太、白水 崇、島田 康人、田中 利男

ゼブラフィッシュを用いた臨床膵癌の個別化医療システム
奥野 真侑子、北原 絵理奈、武内 泰司郎、栗山 直久、伊佐地 秀司、杉村 相子、髙橋 佑佳、高柳 優紀、三上 郁子、笹川 翔太、川原田 みどり、水谷 有香、小岩 純子、島田 康人、西村 有平、田中 利男
2017/10/19 International Symposium on Novel and Sustainable Technology
Zebrafish in Drug Discovery: Disease Models and Chemical Screening for Obesity and Cancer Research
Yasuhito Shimada (Invited speaker)
2017/10/5 Annual Meeting 2017 of The Chem-Bio Informatics Society
In vivo Drug Screening using Cancer Xenograft Zebrafish
Yasuhito Shimada (Focused Session)
2017/8/31-9/1 Innovation Japan 2017
Human Disease Model Zebrafish
Yasuhito Shimada
2017/8/30 The 23rd Japanese Medaka and Zebrafish Meeting
Development of a Zebrafish Model for Type 2 Diabetes Mellitus.
Yasuhito Shimada, Liqing Zang, Norihiro Nishimura
2017/8/6 The 10th Zebrafish Disease Models Meeting
Anti-Cancer Drug Delivery using Supramolecular Coiled-Coil Peptides Formation in Zebrafish Xenograft Model
Yasuhito Shimada, Jian Yang, Rene C.L. Olsthoon, Ewa Snaar-Jagalska, Herman P Spaink, Yuhei Nishimura, Alexander Kros

Zebrafish - a powerful tool to assess anti-obesity effects of natural products
Liqing Zang, Yasuhito Shimada, Norihiro Nishimura
2017/6/16 2017 Midwest Zebrafish Meeting
Development of a Novel Zebrafish Model for Type 2 Diabetes Mellitus
Liqing Zang, Yasuhito Shimada, Norihiro Nishimura






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